Meta-Analysis of Zingiberaceae Interventions on Adult Cognitive Outcomes

A systematic review and meta-analysis of 18 randomized controlled trials evaluating the effects of Zingiberaceae-derived interventions on cognitive outcomes in adults. The work was authored by Desirée Victoria-Montesinos and published on figshare in May 2026. The pooled analysis found a statistically significant improvement in memory-related outcomes, but no significant effects on other cognitive domains.

Use Cases

• Assess the efficacy of curcumin and ginger on memory based on the reported standardized mean difference.
• Inform the design of future clinical trials based on identified limitations like heterogeneity and small study numbers.
• Compare domain-specific cognitive effects (memory vs. executive function) as detailed in the results.
• Evaluate the quality of evidence for Zingiberaceae interventions using the described risk of bias and sensitivity analyses.

Strengths

• Includes 18 randomized, double-blind, placebo-controlled clinical trials.
• Reports a specific, statistically significant effect size for memory outcomes (SMD = 0.57).
• Uses a pre-registered systematic review protocol (PROSPERO CRD420261325966).

Limitations

• The evidence is described as very uncertain due to substantial heterogeneity and a small number of studies.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (18.8 KB), indicating limited scope, likely containing only summary tables or the manuscript.

Provenance

Source

Desirée Victoria-Montesinos

Collection Method

Systematic review and meta-analysis of trials from MEDLINE, Cochrane Central, Web of Science, and Scopus.

Time Range

Literature search from database inception to March 2026.

Freshness

Last updated 2026-05-11 04:26:04; freshness should be verified.