Meta-Analysis of TMS Efficacy for Mild Cognitive Impairment

A systematic review and meta-analysis published in 2026 synthesizes evidence from randomized controlled trials. The dataset, authored by Yongqiang Lin, includes pooled results from 11 RCTs involving 532 participants with mild cognitive impairment. It evaluates the effect of transcranial magnetic stimulation on cognitive domains like global cognition, memory, and executive function.

Use Cases

• Evaluating the pooled efficacy of rTMS on global cognition based on MMSE and MoCA scores
• Analyzing improvements in verbal memory based on AVLT delayed recall and recognition outcomes
• Assessing effects on attention and executive function based on Digit Span and Trail Making Test results
• Comparing treatment effects across different cognitive domains (e.g., naming vs. language fluency)

Strengths

• Includes results from 11 randomized controlled trials with 532 total participants
• Follows a registered PROSPERO protocol (CRD420251274531) and PRISMA guidelines
• Reports specific effect sizes (mean differences and standardized mean differences) with confidence intervals for multiple cognitive domains

Limitations

• Dataset is a 20.0 KB DOCX file; the underlying tabular data structure and column definitions are unknown
• The meta-analysis notes that evidence certainty is mostly moderate due to limited sample sizes
• Row count and specific data fields are not provided, requiring inspection after download

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of RCTs identified from PubMed, CENTRAL, and Embase

Time Range

Studies included through November 10, 2025

Freshness

Last updated 2026-05-18 04:17:12