Daifu Decoction Multi-Omics Data for Ulcerative Colitis Treatment

Figshare dataset from a study by Yangyang Zhao, published in March 2026, investigating the molecular mechanisms of Daifu decoction in treating ulcerative colitis. The data integrates results from a mouse model, including transcriptomics, metabolomics, and 16S rRNA sequencing analyses. It contains tabular data in an XLSX file, though the specific row and column counts are not provided.

Use Cases

• Analyze transcriptomics data to identify key gene targets like PRKCG regulated by Daifu decoction treatment.
• Integrate 16S rRNA sequencing results to correlate changes in gut microbiota diversity with treatment dosage levels.
• Use metabolomics profiles to explore associations between active components and the PKCγ/ERK/NF-κB signaling pathway.
• Cross-reference ELISA and qPCR data on proinflammatory factors with histological staining results to validate therapeutic effects.

Strengths

• Data integrates multiple experimental modalities: transcriptomics, metabolomics, 16S rRNA sequencing, and molecular docking.
• Study includes verification through molecular dynamics simulation, qPCR, western blotting, and immunohistochemistry.
• Dataset is openly available under a CC BY 4.0 license, facilitating reuse.

Limitations

• The dataset is very small at 10.5 KB, indicating limited scope and likely a summary or key results table rather than raw experimental data.
• Data is derived solely from a specific DSS-induced mouse model, limiting direct applicability to human ulcerative colitis.
• Specific sample sizes, row counts, and column structures are not described, hindering assessment of analytical depth.

Provenance

Source

Yangyang Zhao via figshare.

Collection Method

Generated from a controlled laboratory study using a DSS-induced ulcerative colitis mouse model treated with Daifu decoction, analyzed via multi-omics and experimental verification.

Freshness

Last updated March 2026.

Geography

Study conducted in China.