Oropouche Virus Virulence Data in AG129 Mice, 2023-2024

4.9 KB CSV file contains experimental data comparing virulence of historical and contemporary Oropouche virus strains. Ellen Caroline Nobre Santos published the dataset on figshare under a CC-BY-4.0 license, last updated on May 19, 2026. The data likely includes measurements from the AG129 mouse model, such as viremia levels, viral loads in organs, and mortality rates.

Use Cases

• Modeling disease progression based on viremia and mortality data mentioned in the description
• Analyzing viral dissemination patterns based on organ-specific viral load measurements
• Comparing pathogenicity between historical and reassortant virus lineages
• Investigating neuroinvasion capacity based on brain viral load data

Strengths

• Data compares specific virus isolates: historical prototype OROV_BeAn19991 and contemporary reassortants OROV_SC2024 and OROV_AC2024
• Experimental results include multiple measured outcomes: viremia, disease progression, mortality, viral loads across spleen, kidney, liver, lung, uterus, testes, and brain
• Dataset is openly licensed (CC-BY-4.0) for reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is limited to a single mouse model (AG129), which may not fully represent human infection

Provenance

Source

figshare, author Ellen Caroline Nobre Santos

Collection Method

Experimental data from a virology study using the AG129 mouse model

Time Range

Study likely focuses on contemporary isolates from 2023-2024 outbreaks

Freshness

Last updated 2026-05-19 05:41:52; freshness should be verified

Geography

Viruses isolated from non-Amazonian (SC2024) and Amazon Basin (AC2024) regions