Göttingen Minipig UTI Model Data with E. coli Strain Recovery and Characterization

Joyce Lübbers published a study on figshare in May 2026 detailing a novel urinary tract infection model. The research established a 14-day intraurethral infection in minipigs using UPEC strain UTI89, with 75% of animals infected by the challenge strain. Results include bacterial enumeration, agglutination tests, and whole genome sequencing data for recovered strains.

Use Cases

• Evaluating vaccine efficacy against uropathogenic E. coli based on the described minipig infection model.
• Assessing antibiotic treatment outcomes using the bacterial enumeration and strain recovery data.
• Studying bacterial strain persistence and identity verification in animal models based on the agglutination and sequencing results.
• Bridging preclinical findings to human clinical outcomes using the minipig model methodology.

Strengths

• Includes specific quantitative results, such as 75% of animals infected with the challenge strain.
• Describes a 14-day established infection model, providing a clear temporal scope.
• Data is associated with a CC-BY-4.0 license, permitting open reuse.

Limitations

• Dataset scale is limited to 36.0 KB, suggesting a small document rather than a large data repository.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical analysis.

Provenance

Source

figshare

Collection Method

Experimental study involving intraurethral challenge of Göttingen minipigs with UPEC strain UTI89, followed by urine collection, bacterial plating, agglutination testing, and whole genome sequencing.

Time Range

The study period is not specified, but the dataset was last updated in May 2026.

Freshness

Last updated 2026-05-18 05:44:59; freshness should be verified.

Geography

Geographic coverage of the study is not specified.