Meta-Analysis Results on Febuxostat for Renal Transplant Recipients with Hyperuricemia

A meta-analysis document summarizing the effects of febuxostat on uric acid levels and renal function in renal transplant recipients with hyperuricemia. The analysis, authored by Sheng Chao and updated in March 2026, includes results from studies searched up to October 2024. It reports statistical outcomes for changes in uric acid, creatinine, estimated glomerular filtration rate, and other biochemical indices.

Use Cases

• Assess the efficacy of febuxostat in lowering uric acid levels based on reported mean differences.
• Evaluate changes in renal function markers like creatinine and eGFR from the meta-analysis results.
• Analyze the impact on other biochemical indices such as hemoglobin, white blood cells, and liver enzymes.
• Conduct sensitivity analysis on meta-analysis findings for robustness checks.

Strengths

• Includes specific statistical results, such as a mean difference of 129.981 μmol/L for uric acid reduction.
• Reports P-values for all analyzed outcomes, indicating statistical significance levels.
• Document states the quality of included studies was acceptable and no publication bias existed.
• Systematic review is registered with PROSPERO (CRD420261300034).

Limitations

• Dataset is a 17.4 KB DOCX file, indicating a very small scale likely containing only summary tables or text.
• Row count and column definitions are unknown, limiting suitability assessment for direct data analysis.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Sheng Chao via figshare.

Collection Method

Meta-analysis of studies from Web of Science, PubMed, the Cochrane Library, Wan Fang, and CNKI.

Time Range

Studies searched up to 17 October 2024.

Freshness

Last updated 2026-03-17 13:04:42; freshness should be verified.

Geography

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