Herpes Zoster Pain Outcomes Linked to VZV Genotypes and gE Mutations

52 herpes zoster outpatients from Chongqing were enrolled in an integrative immunologic and modeling study. The dataset likely contains viral genotype classifications, glycoprotein E mutation profiles, and associated immunological markers and pain outcomes. Ying Shi authored the study, which was last updated on April 29, 2026.

Use Cases

• Predicting poor pain relief outcomes based on VZV genotype and gE mutation patterns.
• Analyzing associations between specific gE mutations and host immune responses.
• Developing biomarker-based clinical stratification models for herpes zoster patients.
• Studying the distribution and immunological impact of VZV clades in a regional population.

Strengths

• Includes detailed mutation counts, such as an average of 13.46 ± 8.07 mutations.
• Contains immunological indicators like gE antigen, antibody levels, IgG, complement, and CD4+ T cells.
• Predictive model performance metrics are provided, including an AUC of 0.87.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the single-site study in Chongqing.

Provenance

Source

figshare

Collection Method

Clinical data and immunological indicators were collected from patients; VZV genotyping and gE mutation analysis were performed via SNP analysis, PCR, and sequencing.

Freshness

Last updated 2026-04-29 05:58:13; freshness should be verified.

Geography

Chongqing, China