Clinical Trial Data for Gait and Cognitive Function in Cerebral Small Vessel Disease

36 patients with cerebral small vessel disease participated in a randomized controlled trial of accelerated intermittent theta burst stimulation. The dataset includes primary and secondary outcome measures such as 3-meter Timed Up and Go duration, Tinetti, CMMS, and MoCA scores, collected at baseline, post-intervention, and a 4-week follow-up. The data was authored by Xiao-Ying Zhao and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the efficacy of high-dose accelerated intermittent theta burst stimulation based on gait performance metrics like the 3-meter Timed Up and Go test.
• Investigating correlations between neuroimaging phenotypes and treatment response based on features like periventricular white matter hyperintensity and total CSVD burden score.
• Comparing changes in cognitive function between intervention and control groups based on scores from the Chinese Mini-Mental State Examination and Montreal Cognitive Assessment.
• Evaluating the safety and longitudinal effects of non-invasive brain stimulation based on multidimensional function scale scores collected over time.

Strengths

• Data originates from a randomized, single-blind, sham-controlled study, a robust clinical trial design.
• Includes longitudinal measurements from three time points: baseline, post-intervention, and a 4-week follow-up.
• Covers multiple assessment domains including gait, cognitive, affective, and autonomic nervous function.

Limitations

• The dataset is very small at 16.8 KB, indicating limited scope and sample size.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.

Provenance

Source

Xiao-Ying Zhao

Collection Method

Collected as part of a randomized controlled trial.

Freshness

Last updated 2026-06-01 05:24:47; freshness should be verified.