Rab44 Knockout Mouse Data on Ovalbumin-Induced Allergic Airway Inflammation

45.9 KB of experimental data from a study investigating the role of Rab44 in a murine asthma model. The dataset, published under CC-BY-4.0 by Haruka Mawatari, includes results from histopathology, RNA sequencing, degranulation assays, and flow cytometry comparing Rab44-knockout and wild-type mice. It was last updated on 2026-05-21.

Use Cases

• Analyze differential gene expression pathways based on RNA-seq data mentioned in the description
• Compare immune cell infiltration counts based on bronchoalveolar lavage fluid analysis
• Model eosinophil functional defects based on adhesion, migration, and degranulation assay results
• Investigate the role of Rab44 in immune signaling pathways implicated in the study

Strengths

• Data is derived from a controlled experimental model comparing knockout and wild-type mice.
• Analysis includes multiple methodologies: RNA-seq, flow cytometry, and functional cell assays.
• Dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 45.9 KB size suggests a limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments on mice, including RNA sequencing, flow cytometry, and cell culture assays.

Freshness

Last updated 2026-05-21 05:42:45; freshness should be verified.