NHANES 1999–2018 and Hospital Data on Triglyceride-Glucose Index and Melanoma

21,360 participants from the 1999–2018 National Health and Nutrition Examination Survey (NHANES) and 475 patients from three tertiary hospitals were analyzed by Yao Liang. The dataset supports a study investigating the relationship between the triglyceride-glucose (TyG) index and melanoma prevalence and all-cause mortality. It was last updated on March 18, 2026.

Use Cases

• Training machine learning models for melanoma risk prediction based on demographic and metabolic markers like the TyG index.
• Analyzing the U-shaped dose-response relationship between the TyG index and all-cause mortality in melanoma patients.
• Conducting subgroup analyses to verify the robustness of associations between metabolic health and melanoma outcomes.
• Interpreting predictive models using SHAP values to identify key factors like race, age, and serum phosphorus levels.

Strengths

• Includes data from a large, nationally representative survey (21,360 NHANES participants).
• Validates findings with an external hospital-based dataset of 475 melanoma patients.
• Analysis employed multiple machine learning algorithms and model interpretation techniques (SHAP).
• Covers a long time span (1999–2018) for the primary NHANES data.

Limitations

• Row count for the primary dataset is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (11.8 KB), suggesting it may contain summary or processed results rather than raw data.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) and three tertiary hospitals.

Collection Method

Cross-sectional survey data and external hospital-based patient data, analyzed with weighted regression and machine learning.

Time Range

1999–2018 for NHANES data.

Freshness

Last updated 2026-03-18 05:35:02; freshness should be verified.

Geography

United States (NHANES); hospital locations are unspecified.