Mouse Lung Proteome Data for Millettia Speciosa Asthma Treatment Study

179 differentially expressed proteins identified in a mouse model of allergic asthma treated with the herb Millettia speciosa. The dataset includes proteomic analysis results and cytokine profiles from bronchoalveolar lavage fluid, authored by Hangrui Yang and last updated in June 2026. It is a small dataset of 7.2 KB, stored in an XLSX file.

Use Cases

• Identify key protein biomarkers for asthma treatment based on the 179 differentially expressed proteins.
• Study the suppression of Th2-mediated inflammation based on cytokine profiles (IgE, IL-4, IL-5, IL-6).
• Analyze immunometabolic pathway modulation based on functional enrichment results for complement, lipid transport, and PPAR signaling.
• Investigate the CCL24-eosinophil axis in allergic inflammation based on the described proteomic findings.

Strengths

• Includes results for 179 differentially expressed proteins from a high-resolution DIA proteomic analysis.
• Cytokine profiling data for IgE, IL-4, IL-5, and IL-6 is mentioned as being consistent with proteomic findings.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• The dataset is very small at 7.2 KB, indicating limited scope.
• The link to the gut-lung axis is noted as hypothetical and not directly investigated in the source study.

Provenance

Source

figshare, authored by Hangrui Yang.

Collection Method

Generated from high-resolution data-independent acquisition (DIA) lung proteomics integrated with cytokine profiling in an ovalbumin-induced mouse model.

Freshness

Last updated 2026-06-03 07:42:24; freshness should be verified.