Hypothalamic miRNA Expression in Sunite Sheep Under Three Photoperiod Conditions

57, 47, and 12 differentially expressed miRNAs were identified between short, long, and transitional photoperiods in Sunite sheep. The dataset, created by Yajing Shao and last updated in April 2026, contains results from miRNA-sequencing analysis with three biological replicates per condition. Functional annotation links target genes to reproduction-associated pathways like GnRH and prolactin signaling.

Use Cases

• Identify key miRNAs associated with photoperiod changes based on the 57, 47, and 12 differentially expressed miRNAs (DEMs) listed.
• Analyze co-expression networks of miRNAs and target genes based on the described interaction analysis identifying oar-miR-370-5p, oar-miR-10b, and oar-miR-3957-3p.
• Investigate enrichment of biological pathways in seasonal estrus based on the KEGG pathways mentioned, including GnRH and VEGF signaling.
• Compare miRNA expression profiles across specific photoperiod conditions (SP, LP, SLP) based on the experimental design described.

Strengths

• Experimental design includes three distinct photoperiod conditions with three biological replicates per group.
• Analysis identifies specific counts of differentially expressed miRNAs (57, 47, 12) between condition pairs.
• Functional annotation provides concrete pathway associations like GnRH and Wnt signaling.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small at 21.1 KB, indicating limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare, author Yajing Shao.

Collection Method

miRNA-sequencing technology applied to Sunite sheep hypothalamic tissue.

Freshness

Last updated 2026-04-21 05:36:33; freshness should be verified.