Yak Cardiac Transcriptomic and Proteomic Data Under Nutritional Supplementation

Yiqun Chen published an integrative transcriptomic-proteomic atlas of yak cardiac tissue on figshare in April 2026. The dataset contains results from a 60-day study of 12 male Muli yaks, with differential expression analysis yielding 140 DEGs and 254 DEPs. It includes nine-quadrant integration across 4,080 cognate gene-protein pairs.

Use Cases

• Identify biomarkers for nutritional status in ruminants based on the reported discriminatory capacity of GPX1 and SELENOW.
• Analyze post-transcriptional regulatory patterns based on the decoupling between transcriptional and translational landscapes described.
• Study selenoprotein-mediated redox fortification in cardiac tissue based on the coordinated induction of GPX1 and SELENOW.
• Investigate immune quiescence in myocardial responses based on the attenuation of stress-responsive immunosurveillance effectors like ULBP13 and GZMB.

Strengths

• Integrates transcriptomic and proteomic data from the same cardiac tissue samples.
• Provides specific differential expression counts: 140 DEGs and 254 DEPs.
• Includes analysis of 4,080 cognate gene-protein pairs for integration.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (115.7 KB), indicating limited scope or summary-level data.

Provenance

Source

figshare, author Yiqun Chen.

Collection Method

RNA sequencing and data-independent acquisition mass spectrometry on myocardial specimens from a 60-day intervention study with two cohorts.

Time Range

Intervention period of 60 days.

Freshness

Last updated 2026-04-14 12:38:57.

Geography

Qinghai-Tibet Plateau.