Table 4_Old tale new admirers, cetuximab maintenance in metastatic colorectal cancer: a sy

A systematic review and meta-analysis of 6 studies with 727 patients, evaluating the efficacy and safety of cetuximab maintenance therapy for metastatic colorectal cancer. The analysis was conducted by Yici Yan and published on figshare in June 2026. It pools data from PubMed, Embase, Cochrane Library, and Scopus up to March 2026.

Use Cases

• Assessing progression-free and overall survival benefits of cetuximab maintenance therapy based on pooled hazard ratios.
• Comparing treatment efficacy between Asian and non-Asian patient subgroups based on the described subgroup analysis.
• Evaluating the safety profile of cetuximab maintenance by analyzing relative risks of adverse effects like diarrhea and rash.

Strengths

• Includes data from 6 studies encompassing 727 patients, providing a quantitative synthesis.
• Reports specific hazard ratios for progression-free survival (HR: 0.42) and overall survival (HR: 0.47).
• Conducted subgroup analysis by ethnicity, identifying a potential differential benefit for Asian patients.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small (31.4 KB), indicating limited scope and likely summary-level data only.
• The description notes the need for subsequent large-sample, multi-center RCTs to verify conclusions.

Provenance

Source

figshare, authored by Yici Yan.

Collection Method

Systematic literature review and meta-analysis of studies from PubMed, Embase, Cochrane Library, and Scopus.

Time Range

Literature search from database inception to March 2026.

Freshness

Last updated 2026-06-03 06:10:55; freshness should be verified.

Geography

Global, with a noted subgroup analysis for Asian patients.