Platycodin D Effects on Cardiac Hypertrophy and Apoptosis Signaling in Mice

A 409.6 KB Excel file from figshare, authored by Yingrui Li and last updated in 2026, presents experimental data on Platycodin D. The data likely contains results from a mouse model of isoprenaline-induced heart failure, including measurements of cardiac function, hypertrophy, and apoptosis pathway markers across different drug doses.

Use Cases

• Analyzing dose-response relationships of Platycodin D on cardiac function based on the described 12.5, 25, and 50 mg/kg/d treatments.
• Modeling the inhibition of the p53-dependent BCL-2/Bax/caspase-3 signaling pathway based on the described molecular mechanism.
• Comparing therapeutic effects between Platycodin D and the p53 inhibitor pifithrin-α based on the described pharmacological interventions.

Strengths

• Data is associated with a specific, peer-reviewed experimental study described in detail.
• File size of 409.6 KB suggests a focused dataset suitable for targeted analysis.
• Released under the permissive CC-BY-4.0 license, allowing for broad reuse.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (409.6 KB), indicating a limited scope focused on a single study's results.

Provenance

Source

figshare, author Yingrui Li

Collection Method

Experimental data from a mouse model study, likely including measurements from network pharmacology, molecular docking, and pharmacological interventions.

Freshness

Last updated 2026-05-26 06:03:53; freshness should be verified.