Mouse Obesity Study Data on Gut Microbiota and Metabolite Changes

Portulaca oleracea polysaccharide supplementation for 17 weeks reduced obesity in C57BL/6J mice on a high-fat diet. The dataset includes analyzed parameters for obesity, gut microbiota diversity, and serum metabolites like LacCer and NDC. Qiang Fu published this 38.6 KB Excel file on figshare in March 2026 under a CC-BY-4.0 license.

Use Cases

• Train models to predict obesity-related indices based on metabolite levels like LacCer (d18:1/12:0).
• Analyze correlations between specific gut microbiota genera and host metabolic parameters.
• Investigate the impact of polysaccharide interventions on the Firmicutes/Bacteroidetes ratio.
• Validate findings on the relationship between gut microbiota diversity and glucose homeostasis.

Strengths

• Data is derived from a controlled 17-week mouse feeding study with a specific 3.2% POP intervention.
• Analysis includes multiple data types: obesity parameters, gut microbiota sequencing, and serum metabolomics.
• Dataset is openly available under a permissive CC-BY-4.0 license.

Limitations

• Dataset is very small at 38.6 KB, indicating limited scope and likely summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single animal model study, limiting generalizability to other species or conditions.

Provenance

Source

figshare, author Qiang Fu.

Collection Method

Experimental data from a mouse study where C57BL/6J mice were fed a high-fat diet supplemented with Portulaca oleracea polysaccharide for 17 weeks.

Freshness

Last updated 2026-03-18 07:38:47; freshness should be verified.