BNT162b2 Vaccine Proteomic Changes in Qatar: Longitudinal Plasma Data

Qatar-based longitudinal plasma proteomic data from 70 healthy individuals before and after a third BNT162b2 mRNA COVID-19 vaccine dose. Plasma levels of 354 unique proteins were quantified at 3- and 6-months post-booster using Olink technology. The dataset was authored by Sana Bentebbal and last updated on April 24, 2026.

Use Cases

• Identify sustained protein expression changes based on longitudinal proteome profiling over 6 months
• Compare immune response biomarkers between infection-naïve and previously infected individuals
• Investigate inflammatory protein dysregulation post-vaccination based on proteins like PARP-1 and MMP-7

Strengths

• Quantifies 354 unique proteins per sample
• Includes longitudinal data from 70 individuals across three time points
• Distinguishes between 35 infection-naïve and 35 previously infected subjects

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Plasma protein quantification via Olink technology in a longitudinal cohort study.

Time Range

Data collection spans 6 months post-booster vaccination.

Freshness

Last updated 2026-04-24 05:37:11

Geography

Qatar