Systematic Review on Nutrition-Based Prognostic Indices for Breast Cancer

A meta-analysis of 32 reports comprising 13,120 individuals with breast cancer, published up to October 20, 2025. The study evaluates the prognostic utility of the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score. It was authored by Si Chen and uploaded to figshare on May 11, 2026.

Use Cases

• Validate the association between Prognostic Nutritional Index (PNI) and overall survival in breast cancer patients.
• Assess the relationship between Controlling Nutritional Status (CONUT) score and disease-free survival.
• Explore heterogeneity in prognostic evidence for nutrition-based indices across different study settings.
• Inform the design of future clinical studies on composite nutritional-inflammatory markers.

Strengths

• Includes pooled results from 32 studies with a total sample of 13,120 individuals.
• Reports specific hazard ratios (HRs) and odds ratios (ORs) with 95% confidence intervals for key outcomes.
• Conducted systematic searches across four major databases (PubMed, Embase, Web of Science, Cochrane Library).
• Performed subgroup analyses and meta-regression to explore heterogeneity.

Limitations

• The primary data file is a 15.3 KB DOCX document, which is a manuscript summary rather than a raw dataset.
• Row count and column-level documentation for any underlying data are absent.
• Prediction intervals for several analyses crossed the null value, indicating substantial between-study variability.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published studies.

Time Range

Studies from database inception to October 20, 2025.

Freshness

Last updated 2026-05-11 04:18:00