Mouse Weight Gain and Metabolite Data for 2,3-Butanediol Isomer Study

A study by Sunil Veeravalli investigated the effects of 2,3-butanediol isomers on mice fed a fat-enriched diet. The dataset likely contains measurements of weight, plasma and liver metabolite concentrations, and gut microbiota composition for mice under different treatment groups. Results identified 2R,3R-butanediol as preventing weight gain and lowering plasma glucose.

Use Cases

• Analyze the anti-obesogenic effect of 2R,3R-butanediol based on weight gain data from mice on a fat-enriched diet.
• Investigate changes in liver metabolite concentrations based on the identification of indolepropionate, N-delta-acetylornithine, and 1-myristoyl-2-arachidonoyl-glycerophosphorylcholine.
• Study the relationship between gut microbiota composition and plasma glucose levels based on shifts in Bacteroidota and Actinomycetota phyla.
• Compare the efficacy of different 2,3-butanediol isomers based on treatment group data.

Strengths

• Data is derived from a controlled animal study with specific diet and treatment groups.
• Analysis includes multiple data types: weight, plasma metabolites, liver metabolites (693 identified), and gut microbiota composition.
• The dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• The dataset is small (37.4 KB), indicating limited scope and likely a small number of observations.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Experimental study where mice were fed standard or fat-enriched diets and treated with specific 2,3-butanediol isomers.

Freshness

Last updated 2026-05-25 09:59:34; freshness should be verified.