Meta-Analysis of Dietary Nitrate Effects on Weight and Lipid Markers

Eight randomized controlled trials involving 199 participants form the basis of this systematic review and meta-analysis on dietary nitrate supplementation. The analysis, conducted by Wenjun Cai and adhering to PRISMA 2020 guidelines, found significant reductions in systolic blood pressure and lipid markers but no significant effect on body weight or BMI. The underlying data was last updated on April 28, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Conducting a secondary meta-analysis based on the aggregated results from 8 RCTs.
• Investigating the relationship between dietary nitrate and systolic blood pressure based on the reported significant reduction.
• Studying the effect of nitrate supplementation on lipid profiles based on the reported reductions in total cholesterol and triglycerides.
• Assessing publication bias in nutritional intervention studies based on the mention of detected bias for BMI and diastolic blood pressure.

Strengths

• The meta-analysis follows PRISMA 2020 reporting guidelines, suggesting a structured methodology.
• Results include specific statistical measures such as standardized mean differences (SMD), confidence intervals, and I² values for heterogeneity.
• The dataset is openly shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is a 31.4 KB document (DOCX), not a structured data file; the underlying trial data is not directly accessible.
• The meta-analysis includes a relatively small sample size of 199 total participants across 8 studies.
• Column-level documentation for any underlying data is absent; field semantics must be inferred from the manuscript.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials sourced from PubMed, Scopus, Web of Science, and Embase.

Time Range

Literature search conducted up to April 2026.

Freshness

Last updated 2026-04-28 05:24:31