PfSR-X2 Knockdown Effects on P. Falciparum Gene Expression

RNA sequencing data from a study investigating the essential RNA-binding protein PfSR-X2 in Plasmodium falciparum. The dataset, created by Ye Hu and shared under CC-BY-4.0, was last updated on 2026-05-26. It likely contains transcriptomic measurements from conditional knockdown parasites across the intraerythrocytic developmental cycle.

Use Cases

• Analyzing stage-specific gene expression changes based on PfSR-X2 knockdown
• Identifying PfSR-X2-associated transcripts based on RNA immunoprecipitation sequencing
• Studying perturbations in the rif multigene family and ApiAP2 regulatory pathways
• Investigating alternative splicing events in schizont-stage parasites

Strengths

• Data is derived from CRISPR-Cas9-mediated genome editing and RNA sequencing experiments
• Findings are published in a detailed study with specific biological conclusions
• Dataset is shared under a permissive CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 15.8 KB file size suggests a very limited scope, likely summary results rather than raw sequencing data

Provenance

Source

figshare

Collection Method

Generated via CRISPR-Cas9 conditional knockdown, RNA-seq, and RIP-seq experiments in Plasmodium falciparum.

Freshness

Last updated 2026-05-26 08:28:53