Table 4_Thrombomodulin and syndecan-1 and association with lung function in liver transpla

A clinical study dataset from the Danish Comorbidity in Liver Transplant Recipients (DACOLT) study, investigating associations between endothelial damage biomarkers and lung function. The dataset includes 340 liver transplant recipients, with analyses of forced expiratory volume (FEV1), forced vital capacity (FVC), and airflow obstruction. It was authored by Cecilie Cohrt Nebel and last updated on April 13, III.

Use Cases

• Analyze associations between soluble thrombomodulin (TM) levels and lung function metrics (FEV1, FVC) in a transplant cohort.
• Investigate relationships between syndecan-1 (SDC-1) levels and airflow obstruction (FEV1/FVC <0.7) in liver transplant recipients.
• Build regression models to predict pulmonary complications based on endothelial damage biomarker data.
• Conduct comparative analysis of biomarker impact (TM vs. SDC-1) on respiratory outcomes in a specific patient population.

Strengths

• Includes a specific cohort of 340 liver transplant recipients from the DACOLT study.
• Analyses are adjusted for confounders, as stated in the description.
• Biomarker concentrations (TM, SDC-1) are dichotomized using a defined threshold (above the 3rd quartile).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data is unknown, which may limit suitability assessment.
• The study found no significant associations, which may limit predictive modeling utility.

Provenance

Source

figshare, authored by Cecilie Cohrt Nebel.

Collection Method

Clinical study data from the Danish Comorbidity in Liver Transplant Recipients (DACOLT) study, analyzed using linear and logistic regression.

Time Range

null

Freshness

Last updated 2026-04-13 04:31:23; freshness should be verified.

Geography

Denmark (implied by the DACOLT study).