Samantha Kuwada Teixeira published Table 5_Ancestry-informative regulatory variants at KCNB1 modulate adipogenesis and body mass index.xlsx on figshare in May 2026. The 11.4 KB Excel file likely contains results from a genome-wide association study of body mass index in 1,079 admixed Brazilian individuals. The data includes prioritized variants and functional analysis linking a KCNB1 enhancer variant to adipogenesis.
Use Cases
- Identify BMI-associated loci based on GWAS results from an admixed Brazilian cohort.
- Analyze ancestry-enriched regulatory variants, such as rs149309426, mentioned in the description.
- Investigate the functional link between KCNB1 gene regulation and adipocyte differentiation.
- Compare genetic associations across populations using the described variant frequency data.
Strengths
- Data is derived from a genome-wide association study of 1,079 individuals.
- Functional validation includes luciferase assays and mouse knockout models, as described.
- The dataset is licensed under CC-BY-4.0, facilitating open reuse.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is 11.4 KB, indicating a very limited scope, likely a summary table.
Provenance
- Source
- Samantha Kuwada Teixeira
- Collection Method
- Genome-wide association study and integrative functional analysis.
- Freshness
- Last updated 2026-05-07 04:45:01; freshness should be verified.
- Geography
- Admixed Brazilian population