Table 5_Association of NDRG4 gene methylation in peripheral blood leukocytes with gastric

A two-phase case-control study of 310 gastric cancer patients and 300 controls analyzed the association between NDRG4 gene methylation in peripheral blood leukocytes and gastric cancer risk, chemotherapy efficacy, and prognosis. The dataset includes results from bioinformatics analysis of NDRG family genes using TCGA and GEO databases, as well as comparisons of methylation levels across rs7202037 SNP genotypes for 280 patients. The data was uploaded by Zhan Li to figshare and last updated on 2026-04-27.

Use Cases

• Assessing gastric cancer risk based on methylation levels at specific NDRG4 CpG sites mentioned in the description
• Evaluating chemotherapy efficacy in gastric cancer patients based on NDRG4 methylation status
• Analyzing progression-free survival prognosis using NDRG4-chr16:58497239 methylation data
• Investigating the relationship between rs7202037 SNP genotypes and NDRG4 gene methylation levels

Strengths

• Includes data from a two-phase case-control study with 310 patients and 300 controls
• Reports specific odds ratios and confidence intervals for associations between methylation sites and cancer risk
• Links methylation data to clinical outcomes like chemotherapy efficacy and progression-free survival

Limitations

• Dataset is very small at 18.8 KB, indicating limited scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Bioinformatics analysis of TCGA and GEO databases combined with a two-phase case-control study

Freshness

Last updated 2026-04-27 04:12:25; freshness should be verified