Table 5_BKI-1748: Ovine Congenital Toxoplasmosis Treatment Efficacy Results

A research document from figshare details a study on the efficacy of the drug BKI-1748 against congenital toxoplasmosis in pregnant sheep. The study involved 23 infected and 3 uninfected sheep, with treatment initiated 14 days post-infection. Results show a 91% lamb viability rate in treated sheep versus 52% in untreated controls, with only 17% of lambs in the treated group being congenitally infected.

Use Cases

• Analyzing the efficacy of BKI-1748 treatment based on lamb viability and infection rates described in the results.
• Studying the timing of therapeutic intervention based on the protocol of initiating treatment after IgM seroconversion.
• Comparing IgG antibody response dynamics between treated and untreated groups as described in the results section.

Strengths

• The dataset is associated with a specific, peer-reviewed experimental study with clear treatment and control groups (10 treated, 10 untreated infected sheep).
• Results include concrete, quantitative outcomes: 91% lamb viability in treated vs. 52% in untreated, and 17% congenital infection in treated vs. 100% in untreated.

Limitations

• The primary data file is a 171.2 KB DOCX document; the underlying raw data (e.g., individual animal records, column definitions) is not directly accessible.
• Row count and column-level documentation are unknown, which may limit suitability assessment for computational analysis.
• The dataset's scale is very limited, containing results from a single study with 26 total animals.

Provenance

Source

Roberto Sánchez-Sánchez via figshare.

Collection Method

Experimental study involving oral inoculation of pregnant sheep with Toxoplasma gondii oocysts and subsequent drug treatment.

Freshness

Last updated 2026-04-27 05:18:18; freshness should be verified.