Clinical Practice Guidelines for Early Psychosis Intervention: An AGREE II Appraisal

Pasquale Scognamiglio's systematic review and appraisal of 26 international clinical practice guidelines and quality standards for early intervention in psychosis. The work, last updated in June 2026, synthesizes 32 core recommendations for treating clinical high-risk and first-episode psychosis populations. It includes a formal AGREE II quality assessment of the included documents.

Use Cases

• Benchmarking local service components against internationally endorsed recommendations for clinical high-risk psychosis.
• Informing the design of specialized multidisciplinary teams based on the synthesis of guidelines for first-episode psychosis.
• Assessing the methodological quality of clinical guidelines using the AGREE II framework detailed in the review.

Strengths

• Includes 26 distinct clinical documents (24 guidelines and 2 quality standards) published from 2005 onward.
• Synthesizes 32 core recommendations derived from a systematic review following PRISMA 2020 guidance.
• Applies a formal, structured AGREE II appraisal methodology to assess guideline quality.

Limitations

• The dataset is a 19.1 KB DOCX file, indicating a limited scope focused on the review's textual synthesis rather than raw data.
• Row count and column-level documentation are absent; the document's structure must be inspected after download.
• Included documents are limited to English or Italian, which may introduce language and geographic bias.

Provenance

Source

Pasquale Scognamiglio via figshare.

Collection Method

Systematic review of MEDLINE, Cochrane Library, Web of Science, guideline repositories, and grey literature.

Time Range

Guidelines published from 2005 to the search date in March 2025.

Freshness

Last updated 2026-06-03 06:02:24.

Geography

International guidelines, but language is restricted to English or Italian.