Pediatric Central Venous Catheter Thrombosis Risk Factors

A clinical study of 188 critically ill children with central venous catheters identified risk factors for catheter-related thrombosis. The dataset includes 31 thrombosis cases and analyzes variables such as age, catheter type, parenteral nutrition, D-dimer, and fibrinogen levels. A nomogram prediction model was developed with an AUC of 0.952.

Use Cases

• Develop a risk prediction model for CVC-RT using age, parenteral nutrition status, D-dimer, and fibrinogen levels as independent predictors.
• Analyze the incidence rate of thrombosis (16.5%) across different clinical variables like catheter type and patient age.
• Validate the predictive performance of a nomogram model using the 188-patient cohort and its associated clinical data.

Strengths

• Contains data from 188 pediatric patients, providing a specific clinical cohort for analysis.
• Identifies key independent predictors (age, parenteral nutrition, D-dimer, FIB) with a high-performing model (AUC 0.952).
• Focuses on a specific, serious complication (CVC-RT) in a vulnerable population (critically ill children).

Limitations

• Small sample size of 188 patients limits statistical power and generalizability of findings.
• Data is presented in a research paper format (DOCX), not a structured, machine-readable table.
• Geographic and institutional origin of the patient cohort is unspecified, potentially introducing bias.

Provenance

Source

figshare, authored by Xiaolan Zhou.

Collection Method

Clinical data collection from 188 enrolled critically ill pediatric patients with CVCs.

Time Range

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Freshness

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Geography

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