HALP Index and Mortality Across Metabolic Syndrome Spectrum: NHANES 1999-2010

Keting Deng published a dataset on 2026-05-20 containing analysis results linking the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) index to mortality risk. The data is derived from 10,770 adult participants in the U.S. National Health and Nutrition Examination Survey (NHANES) from 1999-2010, with mortality follow-up through 2019. It includes hazard ratios, mortality risk percentages, and model performance metrics from Cox regression and competing-risk analyses.

Use Cases

• Assessing the prognostic value of the HALP index for all-cause and cardiovascular mortality based on the reported hazard ratios and risk percentages.
• Investigating the joint classification of HALP and continuous metabolic syndrome (cMetS) scores for identifying high-risk patient subgroups.
• Evaluating the incremental discrimination of adding HALP to cMetS models using the reported Harrell's C statistic change.
• Analyzing the nonlinear, L-shaped association between HALP levels and mortality risk as described in the results.

Strengths

• Data is based on a large, nationally representative cohort of 10,770 participants from NHANES.
• Analysis includes long-term mortality follow-up through 2019 for participants enrolled between 1999 and 2010.
• Results are supported by multiple statistical methods, including Cox regression, competing-risk models, and an external cohort analysis.

Limitations

• The dataset is very small (17.2 KB), suggesting it contains summary results rather than the underlying individual-level data.
• Column-level documentation is absent; field semantics must be inferred from the research paper description.
• Row count is unknown, which may limit suitability assessment for direct analysis.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) with supportive external cohort evidence.

Collection Method

Survey-weighted Cox regression with restricted cubic splines, adjusted for cMetS and covariates.

Time Range

NHANES data from 1999-2010, with mortality follow-up through 31 December 2019.

Freshness

Last updated 2026-05-20 05:38:42; freshness should be verified.

Geography

United States (NHANES participants).