Systematic Review of Herbst and Twin Block Appliances for Class II Malocclusion

A systematic review and meta-analysis comparing the skeletal, dental, and soft tissue effects of Herbst and Twin Block functional appliances for treating Class II malocclusion in children. The analysis includes seven randomized controlled trials with 548 participants, sourced from databases like PubMed and Scopus up to January 30, 2025. It was authored by Franz Tito Coronel-Zubiate and published on figshare in May 2026.

Use Cases

• Compare treatment efficacy between Herbst and Twin Block appliances based on skeletal, dental, and soft tissue outcomes.
• Inform clinical decision-making for Class II malocclusion management based on meta-analysis results.
• Guide future research by identifying gaps in evidence on functional appliance effectiveness.
• Support evidence-based orthodontic practice guidelines based on standardized mean differences from included RCTs.

Strengths

• Analysis is based on seven randomized controlled trials, a standard for clinical evidence.
• Includes 548 participants, providing a substantial sample size for a meta-analysis in this specialty.
• Employs Cochrane RoB 2.0 and GRADE methods for assessing risk of bias and evidence certainty.
• Search was conducted across multiple major databases (PubMed, Scopus, Web of Science, Cochrane, EMBASE) with no language or date restrictions.

Limitations

• The dataset is a 672.1 KB DOCX document; the underlying extracted data tables are not provided in a machine-readable format.
• Row count and column-level documentation for any extracted data are unknown, limiting direct analysis.
• The analysis is limited to children ≤16 years old, which may not generalize to other age groups.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Time Range

Literature search up to January 30, 2025.

Freshness

Last updated 2026-05-15.