High-Dose Accelerated iTBS Trial for Gait and Cognition in Cerebral Small Vessel Disease

Xiao-Ying Zhao published a dataset from a randomized controlled trial on figshare in June 2026. The dataset likely contains clinical outcome measures from 36 patients with cerebral small vessel disease who received real or sham accelerated intermittent theta burst stimulation. Results include primary and secondary outcomes assessing gait, cognitive, affective, and autonomic nervous function.

Use Cases

• Evaluate the efficacy of high-dose accelerated iTBS based on the 3-meter Timed Up and Go duration outcome.
• Analyze correlations between treatment response and neuroimaging phenotypes based on the CSVD burden score.
• Compare multidimensional functional improvements between intervention groups based on Tinetti, CMMS, and MoCA scores.
• Investigate the safety profile of the intervention based on the described randomized controlled trial design.

Strengths

• Data originates from a randomized, single-blind, sham-controlled clinical trial with 36 participants.
• Includes follow-up evaluations at 4 weeks post-intervention, providing longitudinal outcome data.
• Assesses multiple domains of function including gait, cognition, affect, and autonomic nervous activity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 21.6 KB, indicating limited scope.

Provenance

Source

Xiao-Ying Zhao via figshare

Collection Method

Collected as part of a randomized controlled trial.

Freshness

Last updated 2026-06-01 05:24:48; freshness should be verified.