Table 5_Hybrid plasmids: genetic diversity and hypervirulent phenotype of Klebsiella pneum

32 Klebsiella pneumoniae isolates from patients and environmental surfaces in eight Russian hospitals were whole-genome sequenced. The dataset includes results from a mouse lethality assay for 7 isolates and a cluster analysis of 295 global hybrid plasmids. The data was published by Svetlana Kovalchuk on figshare in April 2026.

Use Cases

• Analyzing the co-occurrence of virulence and resistance genes based on the description of hybrid plasmids.
• Clustering plasmid sequences based on replicon type, ARGs, and virulence genes as described in the global population analysis.
• Investigating the association between specific sequence types (ST147, ST395, ST11) and hybrid plasmid carriage.
• Assessing bacterial virulence phenotypes using mouse lethality assay (LD50) data referenced in the description.

Strengths

• Includes whole-genome sequencing data for 32 bacterial isolates.
• Contains results from a mouse lethality assay for 7 isolates, providing phenotypic virulence data.
• Analyzes a global population of 295 hybrid plasmids for broader context.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the collection from Russian hospitals.

Provenance

Source

figshare

Collection Method

Whole-genome sequencing of clinical and environmental isolates, mouse lethality assay, and bioinformatic cluster analysis.

Time Range

null

Freshness

Last updated 2026-04-29 06:02:25; freshness should be verified.

Geography

Isolates recovered from eight Russian hospitals.