Hypobaric Hypoxia Effects on Lung Dendritic and T-Cell Counts

Figshare data by Xuemei Wei from a 2026 study on high-altitude pulmonary edema. The dataset contains experimental results from rat and mouse models analyzing immune cell responses to hypobaric hypoxia. It includes measurements of lung dendritic cells, CD4+ T cells, and cytokine levels like TNF-α and IL-6.

Use Cases

• Analyze the correlation between hypobaric hypoxia exposure levels and the count of lung dendritic cells in rodent models.
• Model the relationship between TNF-α injection and the proportion of CD4+CD25+ T cells in experimental subjects.
• Compare IL-6 production levels between wild-type and TNF-α-deficient mouse models of HAPE.
• Investigate the protective role of CD4+ T cells by analyzing data from experiments using CD4-neutralizing antibodies.

Strengths

• Data is directly associated with a recent, specific 2026 research publication.
• Includes results from multiple experimental methods: single-cell sequencing, flow cytometry, and in vitro co-culture.
• Explicitly licensed under CC BY 4.0 for clear reuse permissions.

Limitations

• The dataset is small in scale at 976.0 KB, indicating limited raw data volume.
• Sample data and column structure are unavailable, complicating immediate analysis.
• Data is restricted to controlled rodent models, limiting direct applicability to human physiology.

Provenance

Source

Xuemei Wei, via Figshare.

Collection Method

Experimental data from rodent models using single-cell sequencing, flow cytometry, and in vitro co-culture.

Freshness

Last updated on 2026-03-24.