Liubao Tea Multi-Omics Data on Lymphatic Endothelial Cell Metabolism

A 10.6 KB dataset from a 2026 study combining single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking to investigate Liubao tea's effects on lymphatic endothelial cells. The research was conducted by Xiaoxiao Huang and published on figshare. It includes in vitro experimental results verifying the tea extract's impact on cell survival, migration, and gene expression.

Use Cases

• Identify potential therapeutic targets for lymphedema based on multi-omics integration analysis.
• Validate molecular docking predictions of Liubao tea components binding to the PRKCB protein.
• Analyze the relationship between PRKCB expression and the 'inflammation-metabolism' cycle in lymphatic endothelial cells.

Strengths

• Data is derived from a multi-method study combining single-cell analysis, bulk transcriptomics, network pharmacology, and molecular docking.
• Specific experimental results are included, such as a PRKCB fold change of 24.30 and a binding energy of -9.3 kcal/mole for tirilose.

Limitations

• Row count and column-level documentation are absent, requiring manual inspection after download.
• The dataset's 10.6 KB size indicates a limited scope, likely containing summary results rather than raw omics data.

Provenance

Source

Xiaoxiao Huang

Collection Method

Combined computational analysis (single-cell/bulk transcriptomics, network pharmacology, molecular docking) with in vitro cell experiments (CCK-8, wound healing, RT-qPCR).

Freshness

Last updated 2026-05-18 05:38:40.