Esophageal Cancer Treatment Outcomes for 490 T4N0-3M0 Patients

A retrospective cohort of 490 patients with stage T4N0-3M0 esophageal squamous cell carcinoma, comparing survival outcomes between surgery with adjuvant chemoradiotherapy and definitive chemoradiotherapy. The data was collected at a single institution between January 2011 and December 2018 by author Shiwang Wen. It includes overall survival and progression-free survival metrics analyzed before and after propensity score matching.

Use Cases

• Compare overall survival (OS) and progression-free survival (PFS) rates between the S+CRT and dCRT treatment groups.
• Analyze the impact of propensity score matching (PSM) on the survival outcome comparisons for the 138 dCRT and 81 S+CRT matched patients.
• Investigate the association between patient enrollment criteria (T4N0-3M0 stage ESCC) and long-term prognosis across the two treatment modalities.

Strengths

• Includes data from 490 patients with a defined clinical stage (T4N0-3M0 ESCC).
• Reports statistically significant survival outcome comparisons (P-values) for both OS and PFS.
• Applies propensity score matching to control for selection bias between the two treatment groups.

Limitations

• The dataset is very small in file size (19.5 KB), indicating limited raw data or summary statistics only.
• As a single-center study, results may not be generalizable to other populations or healthcare settings.
• Specific patient-level variables and column definitions are unavailable, restricting detailed re-analysis.

Provenance

Source

Shiwang Wen, via figshare.

Collection Method

Single-center retrospective cohort study.

Time Range

January 2011 to December 2018.

Freshness

Data covers patients treated up to December 2018, with the study last updated in March 2026.

Geography

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