Umbrella Review on Periodontal Disease and Obstructive Sleep Apnea

An umbrella review synthesizes evidence from 11 systematic reviews on the association between periodontal disease and obstructive sleep apnea. The document includes methodological quality assessments using AMSTAR-2 and risk of bias evaluations with ROBIS. It covers literature retrieved from 9 databases up to December 2025.

Use Cases

• Extract structured data on the positive association between PD and OSA from the 11 included systematic reviews for meta-analysis.
• Analyze the variability in diagnostic criteria and study design noted in the results section to assess evidence heterogeneity.
• Use the AMSTAR-2 tool evaluations and ROBIS assessments to benchmark the methodological quality of systematic reviews in dental-sleep research.
• Identify gaps for longitudinal research based on the conclusion's note about the observational nature of primary studies.

Strengths

• Focuses on 11 systematic reviews meeting strict inclusion criteria from an initial 217 records.
• Includes critical appraisals using two established tools: AMSTAR-2 for methodological quality and ROBIS for risk of bias.
• Literature search covers 9 major databases, including PubMed and Cochrane, up to December 2025.

Limitations

• Data is presented in a narrative DOCX format (751.4 KB), not a structured, machine-readable table.
• The underlying primary studies are predominantly observational, limiting causal inference as noted in the conclusion.
• Sample size is limited to the conclusions of 11 systematic reviews, not raw patient or study data.

Provenance

Source

figshare, authored by Franz Tito Coronel-Zubiate.

Collection Method

Umbrella review methodology, synthesizing existing systematic reviews after database searches and quality appraisal.

Time Range

Literature covered up to December 2025.

Freshness

Last updated March 2026, with literature coverage up to December 2025.

Geography

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