Platycodin D Effects on Cardiac Hypertrophy and Apoptosis Signaling in Mice

A 95.4 KB Excel file contains data from a study investigating Platycodin D's therapeutic effects on heart failure. Yingrui Li authored this dataset, which was last updated on 2026-05-26. The research used a mouse model to explore dose-dependent improvements in cardiac function and the inhibition of a specific apoptotic pathway.

Use Cases

• Analyzing dose-response relationships of Platycodin D based on the described 12.5, 25, and 50 mg/kg/d treatments.
• Modeling the p53-dependent BCL-2/Bax/caspase-3 signaling pathway interactions mentioned in the study.
• Comparing therapeutic effects between Platycodin D and the p53 inhibitor pifithrin-α as described in the results.

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting broad reuse.
• The study design includes specific dose levels (12.5, 25, 50 mg/kg/d) and a 4-week treatment period, providing structured experimental parameters.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 95.4 KB, indicating limited scope.

Provenance

Source

figshare, author Yingrui Li

Collection Method

Data likely originates from a controlled laboratory study using an isoprenaline-induced heart failure mouse model.

Freshness

Last updated 2026-05-26 06:03:48; freshness should be verified.