Systematic Review Meta-Analysis on Nutrition Indices for Breast Cancer Prognosis

A meta-analysis of 32 reports comprising 13,120 individuals with breast cancer, authored by Si Chen and published on figshare in May 2026. It evaluates the prognostic utility of the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score for outcomes like overall survival and disease-free survival.

Use Cases

• Validate the association between Prognostic Nutritional Index (PNI) and overall survival in breast cancer patients.
• Assess the relationship between Controlling Nutritional Status (CONUT) score and disease-free survival.
• Investigate the link between PNI and pathological complete response (pCR) rates.
• Explore heterogeneity in prognostic marker performance across different study populations.

Strengths

• Includes data from 32 reports and 13,120 individuals, providing a substantial evidence base.
• Reports pooled hazard ratios with 95% confidence intervals for key outcomes like OS and DFS.
• Conducted a systematic search across four major databases (PubMed, Embase, Web of Science, Cochrane Library).

Limitations

• The dataset is a 12.3 KB document; the underlying primary data are not included.
• Prediction intervals for several associations crossed the null value, indicating substantial between-study variability.
• Column-level documentation is absent; field semantics must be inferred from the document text.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published studies.

Time Range

Studies from database inception to 20 October 2025.

Freshness

Last updated 2026-05-11 04:18:06