Gut Microbiota Response to Resistant Dextrin in a 124-Subject Clinical Trial

Caroline Perreau's dataset contains results from a randomized, double-blind, placebo-controlled pilot study on the effects of resistant dextrin on gut microbiota. The study involved 124 healthy male adults categorized by high or low dietary fiber intake, with outcomes measured over a 4-week intervention period. The data was last updated on 2026-05-20 and is shared under a CC-BY-4.0 license.

Use Cases

• Analyzing changes in the relative abundance of the Parabacteroides genus based on fiber supplementation.
• Comparing gut microbiota functional gene activity (e.g., α- and β-glucosidase) between treatment and placebo groups.
• Investigating the differential response to supplementation between high-fiber and low-fiber diet populations.
• Studying correlations between fecal parameters like pH, short-chain fatty acids (SCFAs), and secretory IgA with dietary intervention.

Strengths

• Data originates from a randomized, double-blind, placebo-controlled trial, a rigorous study design.
• Includes results from 124 subjects with a mean age of 36.2 ± 11.6 years, providing a specific demographic context.
• Reports specific, statistically significant findings, such as an increase in Parabacteroides abundance from 1.4% to 5.5% with active supplementation.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (20.2 KB), indicating limited scope, likely containing summary results rather than raw individual-level data.

Provenance

Source

Caroline Perreau via figshare.

Collection Method

Data collected from a randomized, double-blind, placebo-controlled clinical trial (NCT05105425).

Time Range

The intervention period was 4 weeks, with follow-up measurements 2 weeks post-intervention.

Freshness

Last updated 2026-05-20 16:01:29; freshness should be verified.