Table 6_A comparative study of the gut microbiome and fecal metabolome in hypertensive pat

Daqing and Haikou, China, are the geographic focus of this dataset comparing gut microbial and metabolic profiles in hypertensive patients from distinct climatic regions. It contains results from shotgun metagenomic sequencing and untargeted metabolomics on fecal samples from 60 patients, collected between May and December 2024. The data was authored by Shuyue Liu and shared under a CC-BY-4.0 license.

Use Cases

• Identify differentially abundant microbial genera associated with geographic location based on ALDEx2 analysis.
• Analyze dysregulated metabolic pathways like glycerophospholipid metabolism and ABC transporters from metabolomic results.
• Build predictive models for geographic origin using microbial features, as demonstrated by the logistic regression model with an AUC of 0.8069.
• Investigate correlations between specific differential microbes and metabolites, such as Pseudescherichia and 15-HETE.

Strengths

• Includes data from 60 hypertensive patients (28 from Daqing, 32 from Haikou) with paired metagenomic and metabolomic profiles.
• Analysis adjusted for key confounders including age, BMI, smoking, and drinking status.
• Identifies 34 differentially abundant genera and 38 differentially abundant metabolites with specific examples like ginsenoside Rg3.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (42.1 KB), indicating a limited scope focused on summary results rather than raw sequencing data.

Provenance

Source

figshare, author Shuyue Liu.

Collection Method

Cross-sectional study using shotgun metagenomic sequencing and untargeted metabolomics on fecal samples.

Time Range

Samples collected between May and December 2024.

Freshness

Last updated 2026-05-22 05:37:07; freshness should be verified.

Geography

Daqing (middle-temperate climate) and Haikou (tropical climate), China.