Table 6_ANCA-associated vasculitis is associated with an increased risk of cardiac and vas

A retrospective cohort study of 26,329 patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) and matched controls from the US-based TriNetX network. The dataset contains results analyzing the increased risk of death and cardiovascular events in ANCA-associated vasculitis, including hazard ratios for outcomes like MACE and thromboembolic events. The study was authored by Sebastian Klapa and last updated on 2026-04 15.

Use Cases

• Validate the association between ANCA-associated vasculitis and cardiovascular morbidity based on reported hazard ratios.
• Compare mortality and cardiovascular event risks between GPA and MPA patient subgroups based on the study's findings.
• Benchmark clinical outcomes for vasculitis patients against a propensity-matched control cohort described in the methods.

Strengths

• Includes a large cohort of 20,422 GPA and 5,907 MPA patients.
• Uses a 1:1 propensity-matched control cohort for comparability.
• Reports specific hazard ratios for mortality, MACE, and thromboembolic events.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small (26.9 KB), suggesting it likely contains summary results rather than raw patient-level data.
• Data may reflect geographic and source bias inherent to the US-based TriNetX network.

Provenance

Source

Electronic health records database of the US-based TriNetX network.

Collection Method

Retrospective cohort study using propensity score matching and Cox regression analysis.

Time Range

null

Freshness

Last updated 2026-04-15 05:45:59; freshness should be verified.

Geography

United States (based on the TriNetX network).