Table 6_Association between circulating biomarkers of one-carbon metabolism and glymphatic

210 participants, including 68 with normal cognition, 75 with mild cognitive impairment due to AD, and 67 with dementia due to AD, were enrolled in this study. The dataset, authored by Yali Chen and last updated in May 2026, contains measurements of circulating biomarkers and neuroimaging indices to explore their association with cognitive performance.

Use Cases

• Correlating serum folate levels with glymphatic function based on the DTI-ALPS index
• Comparing biomarker profiles across cognitive groups (NC, AD-MCI, AD-D)
• Investigating sex or age subgroup differences in biomarker associations
• Modeling the combined risk of low folate and low DTI-ALPS index on cognitive scores

Strengths

• 210 participant records with clinical stratification
• Includes multiple biomarker types (folate, B12, homocysteine) and a neuroimaging index
• Results include specific p-values and correlation coefficients for key findings

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small at 23.4 KB, indicating limited scope

Provenance

Source

Yali Chen

Collection Method

Clinical study enrolling participants and measuring serum biomarkers and neuroimaging indices.

Freshness

Last updated 2026-05-11 04:29:23; freshness should be verified