Clinical Practice Guidelines for Early Psychosis Intervention: An AGREE II Appraisal

A 2025 systematic review and appraisal of 26 international clinical practice guidelines and quality standards for early intervention in psychosis (EIP). The dataset, a 17.7 KB DOCX file, synthesizes 32 core recommendations for clinical high-risk and first-episode psychosis populations, authored by Pasquale Scognamiglio.

Use Cases

• Benchmarking local service components against internationally endorsed recommendations for early psychosis care.
• Informing the development of new clinical guidelines based on synthesized evidence from 26 source documents.
• Analyzing methodological quality variations in guideline development using AGREE II domain scores.
• Identifying consensus treatment components, such as specialized multidisciplinary teams and family interventions, for service planning.

Strengths

• Includes 26 source documents (24 clinical practice guidelines and 2 quality standards) providing a broad evidence base.
• Applies the standardized AGREE II methodology for quality appraisal, with inter-rater agreement assessed.
• Synthesizes 32 core recommendations, identifying components endorsed by at least one-third of relevant documents.
• Released under a permissive CC-BY-4.0 license, facilitating reuse and sharing.

Limitations

• The 17.7 KB file size suggests the dataset is a summary document; the underlying extracted data or full appraisal matrices are not included.
• Row count and column-level documentation are unknown, limiting assessment of the structured data's granularity.
• The description focuses on the review's findings; the specific data format and variables within the DOCX file are not detailed.

Provenance

Source

Systematic review of MEDLINE (via PubMed), Cochrane Library, Web of Science, guideline repositories, and grey literature.

Collection Method

Systematic review and AGREE II-based appraisal conducted in accordance with PRISMA 2020 guidance.

Time Range

Guidelines and standards published from 2005 onward, searched up to March 2025.

Freshness

Last updated 2026-06-03 06:02:23.

Geography

International (documents published in English or Italian).