Multi-Omics Data on Daifu Decoction in Ulcerative Colitis Mouse Model

Experimental data from a study investigating the molecular mechanisms of Daifu decoction (DFD) in treating ulcerative colitis. The dataset includes results from transcriptomics, metabolomics, 16S rRNA sequencing, and molecular docking simulations from a mouse model. It is a small, focused dataset provided in a 21.0 KB XLSX file.

Use Cases

• Analyze transcriptomics data to identify key targets like PRKCG regulated by Daifu decoction treatment.
• Correlate 16S rRNA sequencing results on gut microbiota diversity with proinflammatory factor levels from ELISA data.
• Use metabolomics and molecular docking simulation data to validate binding of DFD active components to the PRKCG target.
• Examine qPCR and western blotting data to study the PKCγ/ERK/NF-κB signaling pathway regulation.

Strengths

• Integrates multiple data types: transcriptomics, metabolomics, 16S rRNA sequencing, and molecular simulations.
• Dataset is openly licensed under CC BY 4.0, facilitating reuse and sharing.
• Study design includes experimental verification via qPCR, western blotting, and immunohistochemistry.

Limitations

• Very small dataset at 21.0 KB, limiting the scope for large-scale statistical or machine learning analysis.
• Data is derived from a single, controlled mouse model study, which may not generalize to human biology.
• Specific row and column counts are unknown, making it difficult to assess the dataset's structure and volume.

Provenance

Source

figshare, authored by Yangyang Zhao.

Collection Method

Data generated from a laboratory study using a DSS-induced ulcerative colitis mouse model treated with Daifu decoction.

Freshness

Last updated on 2026-03-24.