Table 6_HALP: HALP Index and Mortality Risk Across Metabolic Syndrome Spectrum

Keting Deng published a dataset on 2026-05-20 containing results from a study of 10,770 NHANES participants (1999–2010) followed through 2019. It examines the association between the Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) index, a routine nutrition-inflammation marker, and all-cause and cardiovascular mortality across the continuous metabolic syndrome (cMetS) spectrum. The dataset includes hazard ratios, mortality risk percentages, and model performance metrics from the analysis.

Use Cases

• Assessing the prognostic value of the HALP index for mortality based on the reported hazard ratios and risk percentages.
• Investigating the joint effect of metabolic burden (cMetS) and systemic vulnerability (HALP) on mortality outcomes.
• Evaluating model discrimination improvement by adding HALP to a baseline model using the reported Harrell's C statistic change.
• Analyzing the nonlinear, L-shaped association between a composite biomarker and health outcomes.

Strengths

• Data is derived from a large, nationally representative cohort of 10,770 participants.
• Analysis includes long-term follow-up through 2019 for participants enrolled between 1999 and 2010.
• Results are supported by external cohort validation, as mentioned in the description.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analysis dataset is unknown, which may limit suitability assessment.
• The primary file format is DOC, which is not a standard format for structured data analysis.

Provenance

Source

NHANES (National Health and Nutrition Examination Survey) with supportive external cohort evidence.

Collection Method

Survey-weighted Cox regression and competing-risk models applied to cohort data.

Time Range

NHANES data from 1999–2010, with mortality follow-up through 31 December 2019.

Freshness

Last updated 2026-05-20 05:38:43; freshness should be verified.

Geography

United States (NHANES).