Systematic Review Comparing Herbst and Twin Block Appliances for Class II Malocclusion

A systematic review and meta-analysis authored by Franz Tito Coronel-Zubiate, comparing the skeletal, dental, and soft tissue effects of Herbst and Twin Block appliances in children with Class II malocclusion. The analysis includes seven randomized controlled trials with 548 participants, sourced from PubMed, Scopus, Web of Science, and other databases up to January 30, 2025. The file was last updated on May 15, 2026.

Use Cases

• Compare the effectiveness of Herbst and Twin Block appliances based on skeletal, dental, and soft tissue outcomes.
• Inform clinical decision-making for Class II malocclusion management based on meta-analysis results.
• Assess the certainty of evidence for functional appliance treatments using GRADE methodology.
• Guide future research by identifying gaps in comparative effectiveness studies of orthodontic appliances.

Strengths

• The meta-analysis is based on seven randomized controlled trials, a rigorous study design.
• The review includes 548 participants, providing a substantial sample size for analysis.
• A comprehensive search was conducted across multiple major databases with no language or date restrictions.
• Risk of bias was formally assessed using the Cochrane RoB 2.0 tool.

Limitations

• The dataset is a single 673.9 KB DOCX document, which is a very small text file.
• The underlying data tables, column definitions, and raw participant-level data are not provided.
• The scope is limited to the specific research question of comparing two orthodontic appliances.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Time Range

Studies searched up to January 30, 2025.

Freshness

Last updated 2026-05-15 07:47:32; freshness should be verified.