Long-Term Trends in Leukemia Subtype Burden in China, 1990-2021

GBD 2021 data provides estimates for the burden of four leukemia subtypes in China from 1990 to 2021. The analysis includes 105,670 estimated new cases in 2021 and uses Joinpoint regression and age-period-cohort modeling to assess trends and project future incidence. Author Yudi Shangguan published the findings on figshare under a CC-BY-4.0 license.

Use Cases

• Analyze long-term incidence trends for acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL) based on the described time-series data.
• Project future leukemia subtype incidence rates through 2046 based on the described Bayesian age-period-cohort modeling.
• Assess the contribution of risk factors like smoking and high body-mass index to leukemia disability-adjusted life years (DALYs) based on the described GBD analysis.
• Compare age and sex-stratified burden patterns across leukemia subtypes based on the described demographic stratification.

Strengths

• Data spans 31 years (1990-2021) for longitudinal analysis.
• Includes estimates for four distinct leukemia subtypes (AML, CML, ALL, CLL).
• Analysis incorporates multiple statistical methods: Joinpoint regression, age-period-cohort modeling, and Bayesian projections.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (27.6 KB), suggesting it contains summary statistics rather than raw case-level data.

Provenance

Source

Global Burden of Disease (GBD) 2021 database.

Collection Method

Joinpoint regression, age-period-cohort modeling, and Bayesian age-period-cohort modeling applied to GBD estimates.

Time Range

1990 to 2021, with projections to 2046.

Freshness

Last updated 2026-06-04 04:32:11; freshness should be verified.

Geography

China.