Hypothalamic miRNA Expression in Sunite Sheep Under Three Photoperiods

57 differentially expressed miRNAs were identified between short and long photoperiods in Sunite sheep. This 21.0 KB Excel dataset contains miRNA sequencing results from a study by Yajing Shao, uploaded to figshare in April 2026. The data reveals miRNA profiles associated with seasonal estrus and targets enriched in reproductive signaling pathways.

Use Cases

• Identify differentially expressed miRNAs based on photoperiod conditions described in the study
• Analyze co-expression networks of miRNAs and their predicted target mRNAs
• Investigate enrichment of target genes in KEGG pathways like GnRH, prolactin, VEGF, and Wnt signaling
• Validate candidate miRNAs such as oar-miR-370-5p, oar-miR-10b, and oar-miR-3957-3p for functional studies

Strengths

• Data is derived from miRNA sequencing with three biological replicates per photoperiod group, suggesting experimental rigor
• The description provides specific counts of differentially expressed miRNAs (57, 47, 12) between comparison groups
• Functional annotation links target genes to specific, biologically relevant KEGG pathways
• Dataset is openly available under a CC-BY-4.0 license

Limitations

• Row count and column-level documentation are unknown; field semantics must be inferred after download
• The dataset is very small at 21.0 KB, indicating limited scope or summary-level data
• Data may reflect bias inherent to the specific Sunite sheep breed and experimental conditions

Provenance

Source

figshare, author Yajing Shao

Collection Method

miRNA sequencing analysis of hypothalamic tissue from Sunite sheep under controlled photoperiod conditions

Time Range

Experimental time range is not specified in the provided metadata

Freshness

Last updated 2026-04-21 05:36:32; freshness should be verified

Geography

Study likely conducted in a research setting, but specific geographic coverage is not stated