Sea Urchin Immune Cell Transcriptional Response to UVB-Induced DNA Damage

Transcriptional data from purple sea urchin immune cells exposed to UVB radiation, collected by Riss M. Kell and published on figshare in March 2026. The dataset likely contains gene expression profiles from single-cell RNA sequencing at six hours post-exposure, identifying responses in phagocytes and vibratile cells.

Use Cases

• Analyze conserved DDR gene activation based on transcriptional response data
• Identify cell-type-specific mediators of genotoxic stress based on single-cell RNA sequencing results
• Study the link between autophagy and ubiquitin signaling pathways based on functional assay results
• Compare damage recognition systems in echinoderms based on the absence of vertebrate-specific DNA sensors

Strengths

• Data is derived from a long-lived, cancer-resistant model organism diverged from vertebrates ~550 million years ago
• Includes results from functional assays and western blots confirming pathway modifications
• Published under a CC-BY-4.0 license for open reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Sample data is unavailable for preview

Provenance

Source

figshare

Collection Method

Single-cell RNA sequencing and functional assays on purple sea urchin immune cells exposed to UVB radiation.

Freshness

Last updated 2026-03-19 05:18:35