aMAP Score Association with Mortality in MASLD/MetALD/ALD Patients: NHANES 1999-2018

32,654 participants from the National Health and Nutrition Examination Survey (NHANES) 1999-2018 were analyzed to assess the association between the aMAP risk score and mortality in patients with steatotic liver disease. The dataset, authored by Peng-yang Li and last updated in 2026, includes results from multivariable Cox models and Kaplan-Meier analyses, with external validation from a Southern Chinese cohort of 642 individuals. It reports hazard ratios for all-cause, cardiovascular, and cancer mortality across MASLD, MetALD, and ALD subclassifications.

Use Cases

• Validate the aMAP score as a mortality predictor based on the reported hazard ratios for all-cause, cardiovascular, and cancer death.
• Study non-linear risk relationships based on the restricted cubic spline analysis described in the results.
• Assess risk stratification performance across steatotic liver disease subtypes (MASLD, MetALD, ALD) based on the cohort study findings.
• Conduct external validation of clinical risk scores using the described independent hospital-based cohort.

Strengths

• Large primary cohort of 32,654 participants from a nationally representative survey (NHANES).
• Includes external validation from an independent hospital-based cohort of 642 individuals.
• Analyses multiple mortality outcomes (all-cause, cardiovascular, cancer) and reports specific hazard ratios.
• Uses established statistical methods (Cox models, Kaplan-Meier, Fine-Grey competing risk) as described.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analytical dataset is unknown, which may limit suitability assessment.
• The 21.1 KB file size suggests the dataset is likely a summary document or table, not the raw patient-level data.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) and an independent hospital-based Southern Chinese cohort.

Collection Method

Cohort study using multivariable Cox proportional hazards models and other statistical analyses.

Time Range

NHANES data from 1999 to 2018, with mortality follow-up through December 31, -2019.

Freshness

Last updated 2026-04-24 13:49:18; freshness should be verified.

Geography

United States (NHANES) and Southern China (validation cohort).