Liubao Tea Multi-Omics Analysis of Lymphatic Endothelial Cell Metabolism

A 67.1 KB Excel dataset from a 2026 study analyzing the effects of Liubao tea extract on human lymphatic endothelial cells. The data combines single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking results. It was authored by Xiaoxiao Huang and shared under a CC-BY-4.0 license.

Use Cases

• Validate potential therapeutic targets based on the identified overlapping gene PRKCB.
• Analyze protein-protein interaction networks based on the reported interactions between PRKCB, IKBKB, PIK3CG, and GSK3B.
• Perform molecular docking simulations based on the reported binding affinities of Liubao tea components like tirilose.
• Investigate gene expression changes in cell function assays based on the reported downregulation of PRKCB and upregulation of PROX1 mRNA.

Strengths

• Data integrates results from multiple high-throughput analysis methods, including single-cell and bulk transcriptomics.
• Specific molecular findings are reported, such as a fold change of 24.30 for PRKCB expression and a binding energy of -9.3 kcal/mole for a key component.

Limitations

• The dataset is small (67.1 KB), suggesting limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Combined computational analysis (single-cell transcriptomics, bulk transcriptomics, network pharmacology, molecular docking) with in vitro cell experiments (CCK-8, wound healing, RT-qPCR).

Freshness

Last updated 2026-05-18 05:38:39; freshness should be verified.